Dr. Jacobs grew up in Washington and Idaho watching his mother valiantly battle colorectal cancer for 24 years. She is his inspiration for becoming an oncologist. He graduated summa cum laude from Brigham Young University. He subsequently attended UT Southwestern Medical Center where he graduated top of his class and received his MD with Distinction in Research. Dr. Jacobs later completed specialty training in Radiation Oncology at Duke University. During his training he received prestigious national and international awards.
Dr. Jacobs has co-authored peer-reviewed manuscripts for a variety of cancer sites including prostate, breast, lung, gastrointestinal, genitourinary, gynecologic, brain, head and neck, and lymphoma. He is experienced in advanced radiation techniques including intensity-modulated radiation therapy (IMRT), image-guided radiation therapy (IGRT), stereotactic body radiation therapy (SBRT), stereotactic ablative radiotherapy (SABR), and stereotactic radiosurgery (SRS).
His hobbies include cycling, hiking, paddle boarding, basketball, pickleball, bowling, disc golf, and spending time with his wife, three children, and two dogs.
Education
Undergraduate:
- Brigham Young University; Provo, UT
Medical School:
- University of Texas Southwestern; Dallas, TX
Internship:
- Gundersen Health Systems; La Crosse, WI
Residency:
- Duke University (Radiation Oncology); Durham, NC
Other:
- Gamma Knife Radiosurgery Course at the University of Pittsburgh; Pittsburgh, PA
Certification
- American Board of Radiology: Radiation Oncology
Honors & Memberships
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Chief Radiation Oncology Resident, Duke University (2019-2020)
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Presented more than 20 abstracts at national and international conferences, earning multiple awards including Best Abstract, Best Poster, Travel Grant and 9 Oral Presentations (2013-2019)
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Graduated #1 of 242 medical students at University of Texas Southwestern (2015)
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Physicians of Tomorrow Award, American Medical Association Foundation (2014)
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Tylenol ‘Future Care’ Scholar - 1 of 10 chosen nationally (2012)
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Graduate Scholar Award, Golden Key International Honor Society (2012)
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Graduated Summa Cum Laude - top 1% of his class at Brigham Young University (2011)
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Alpha Omega Alpha Honor Medical Society
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American Board of Radiology (ABR)
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American Society of Radiation Oncology (ASTRO)
Textbook Chapters
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Jacobs CD, Moravan MJ, Choe J, Kahmke R, Mowery YM, Salama JK. Elsevier. Cancers of the Oral Cavity: Diagnosis and Treatment. Encyclopedia of Cancer, 3rd Edition. 2019: 131-168.
Peer-Reviewed Articles
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Kabarriti R, Lloyd S, Jabalee J, Gay LM, Slater T, Guzman K, Jacobs CD, Inocencio S, Lin R, Nguyen C, MacEwen I, Crawford AH, Rutenberg M, Singh J, Ross J, Kim-Wang S, Matthiesen C, Neff K, Liu GF, Juarez TM, Liaw SL. Resolving Clinically Indeterminate Findings During Anal Cancer Surveillance with TTMV-HPV DNA. Cancers. 2026 Jan; 18(1):35.
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Kabarriti R, Lloyd S, Jabalee J, Del Vecchio Fitz C, Tao R, Slater T, Jacobs CD, Inocencio S, Rutenberg M, Matthiesen C, Neff K, Liu G, Juarez TM, Liaw SL. Evaluating Tumor Tissue-Modified Viral (TTMV)-HPV DNA for the Early Detection of Anal Squamous Cell Carcinoma Recurrence. Cancers. 2025 Jan; 17(2):174.
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Jacobs CD, Barak I, Jung SH, Rocke DJ, Kahmke RR, Suneja G, Mowery YM. Prediction model to estimate overall survival benefit of postoperative radiotherapy for resected major salivary gland cancers. Oral Oncology. 2022 Sept; 132:105955.
- Shenker RF, Price JG, Jacobs CD, Palta M, Czito BG, Mowery YM, Kirkpatrick JP, Boyer MJ, Oyekunle T, Niedzwiecki D, Song H, Salama JK. Comparing Outcomes of Oligometastases Treated with Hypofractionated Image-Guided Radiotherapy (HIGRT) with a Simultaneous Integrated Boost (SIB) Technique versus Metastasis Alone: A Multi-Institutional Analysis. Cancers. 2022 May; 14(10):2403.
- Jacobs CD, Mehta K, Gao J, Wang X, Salama JK, Kelsey CR, Torok JA. Nomogram Predicting Overall Survival Benefit of Stereotactic Ablative Radiotherapy for Early-Stage Non-Small Cell Lung Cancer. Clinical Lung Cancer. 2022 Mar; 23(2):177-184.
- Jacobs CD, Williamson H, Barak I, Rocke DJ, Kahmke RR, Suneja G, Mowery MM. Postoperative Radiotherapy is Associated with Improved Overall Survival for Alveolar Ridge Squamous Cell Carcinoma with Adverse Pathologic Features. Head & Neck. 2021 Jan; 43(1):203-211.
- Subashi E*, Jacobs CD*, Hood R, Kirsch DG, Craciunescu O. A design process for a 3D printed patient-specific applicator for HDR brachytherapy of the orbit. 3D Printing in Medicine. 2020 Jun; 6(1):15. *Co-first author.
- Jacobs CD, Gao J, Wang W, Ready NE, Clarke JM, Tong B, Suneja G, Kelsey CR, Torok JA. Definitive Radiotherapy for Inoperable Stage IIB Non-Small Cell Lung Cancer: Patterns of Care and Comparative Effectiveness. Clinical Lung Cancer. 2020 May; 21(3):238-246.
- Song EJ, Jacobs CD, Palta M, Willett CG, Yuan W, Czito BG. Evaluating Treatment Protocols for Rectal Squamous Cell Carcinomas: the Duke Experience and Literature Review. Journal of Gastrointestinal Oncology. 2020 Apr; 11(2):242-249.
- Jacobs CD, Trotter J, Palta M, Yuan W, Willett CG, Lee WR, Czito BG. Multi-Institutional Analysis of Synchronous Prostate and Rectosigmoid Cancers. Frontiers in Oncology. 2020 Mar; 10:345.
- Chodavadia P*, Jacobs CD*, Wang F, Havrilesky LJ, Chino JP, Suneja G. Off-Study Utilization of Experimental Therapies: Analysis of GOG249-Eligible Cohorts Using Real World Data. Gynecologic Oncology. 2020 Jan; 156(1):154-16. *Co-first author.
- Barbour AB*, Jacobs CD*, Williamson H, Floyd SR, Suneja G, Torok JA, Kirkpatrick JP. Radiotherapy Practice Patterns for Brain Metastases in the United States in the Stereotactic Radiosurgery Era. Advances in Radiation Oncology. 2020 Jan; 5(1):43-52. *Co-first author.
- Jacobs CD, Palta M, Willett CG, Czito BG. Perioperative Systemic Therapy Versus Neoadjuvant Chemoradiotherapy for Operable Gastroesophageal Junction Cancers. ASCO Daily News. 2019 Oct.
- Carpenter DJ, Jacobs CD, Wong T, Craciunescu O, Chino JP. Changes on Mid-Chemoradiotherapy FDGPET/CT for Cervical Cancer are Associated with Prognosis. International Journal of Radiation Oncology ∙ Biology ∙ Physics. 2019 Oct; 105(2):356-366.
- Corradetti MN, Torok JA, Hatch AJ, Xanthopoulos EP, Lafata K, Jacobs CD, Rushing C, Calaway J, Jones G, Kelsey CR, Nixon AB. Dynamic Changes in Circulating Tumor DNA During Chemoradiation for Locally Advanced Lung Cancer. Advances in Radiation Oncology. 2019 Oct; 4(4):748-52.
- Jacobs CD, Palta M, Williamson H, Price JG, Czito BC, Salama JK, Moravan MJ. Hypofractionated Image- Guided Radiation Therapy with Simultaneous-Integrated Boost Technique for Limited Metastases: A Multi- Institutional Analysis. Frontiers in Oncology. 2019 Jun; 9:469.
- Natarajan BD, Jacobs CD, Salama JK. Radiotherapy and Small Cell Carcinoma with Paraneoplastic Polyneuropathy. Annals of Internal Medicine. 2019 Sep; 171(6):440-441.
- Jacobs CD, Carpenter DJ, Hong JC, Havrilesky L, Sosa JA, Chino JP. Radiation Records in the National Cancer Database: Variations in Coding and/or Practice Significantly Alters Survival Results. JCO Clinical Cancer Informatics. 2019 May; 3:1-9.
- Jacobs CD, Horton J, Blitzblau R, Suneja GS. Synchronous Breast Cancer and Primary Mediastinal B-cell Lymphoma. Practical Radiation Oncology. 2019 Mar; 9(2): featured on the cover.
- Jacobs CD, Barbour AB, Mowery YM. The Relative Distribution of Oral Cancer in the United States by Subsite. Oral Oncol. 2019 Feb; 89:56-58.
- Jacobs CD, Chino JP, Suneja GS. Locally Advanced Cervical Cancer Invading the Rectum and Bladder. Practical Radiation Oncology. 2019 Jan; 9(1): featured on the cover.
- Jacobs CD, Eickstaedt N, Driscoll C. Multiple Primary Synchronous Lung Cancer Diagnosed by Routine Low-Dose Computed Tomography Screening and Treated with Stereotactic Body Radiation Therapy. Gundersen Medical Journal. 2017 Dec; 10(1):61.
- Nashed D*, Jacobs CD*, Hagan B. Positional Cough: the Presenting Symptom of Left Atrial Myxoma. Gundersen Medical Journal. 2017 Dec; 10(1):50. *Co-first author.
- Jacobs CD, Jafari ME. Early Results of Lung Cancer Screening and Radiation Dose Assessment by Low- Dose CT at a Community Hospital. Clinical Lung Cancer. 2017 Feb; 18(5):E327-E331.
- Jacobs CD. "Ask About Safety Caps." Institute for Safe Medication Practices Medication Safety Alert! Acute Care. 2016 Mar;21(6):2.
- Jacobs CD, Tumati V, Kapur P, Yan J, Xie X, Hannan R, Hsieh JT, Kim DW, Saha D. Pretreatment Biopsy Analysis of DAB2IP Identifies Subpopulation of High-Risk Prostate Cancer Patients with Worse Survival Following Radiation Therapy. Cancer Medicine. 2015 Dec;4(12):1844-52.
- Singla N, Gayed BA, Bagrodia A, Krabbe LM, Palazzi KL, Mirheydar H, Harrow B, Jacobs CD, Youssef R, Darwish O, Sagalowski A, Lotan Y, Derweesh I, Margulis V. Multi-Institutional Analysis of Renal Function Outcomes Following Radical Nephroureterectomy and Partial Ureterectomy for Upper Tract Urothelial Carcinoma. Urologic Oncology: Seminars and Original Investigations. 2015 Jun;33(6):268.e1-7.
- Jacobs CD, Tumati V, Yan J, Kapur P, Xie X, Pistenmaa D, Bhuiyan M, Yu L, Hsieh JT, Saha D, Kim DW. DOC-2/DAB2 Interacting Protein Status in High-Risk Prostate Cancer Correlates with Outcome for Patients Treated with Radiation Therapy. International Journal of Radiation Oncology ∙ Biology ∙ Physics. 2014 Jul; 89(4):729-735.
- Jacobs CD, Chun S, Yan J, Xie X, Pistenmaa D, Hannan R, Lotan Y, Roehrborn C, Choe K, Kim DWN. Aspirin Improves Outcome in High Risk Prostate Cancer Patients Treated with Radiation Therapy. Cancer Biology & Therapy. 2014 Jun; 15(6):699-706.
- Krabbe LM, Bagrodia A, Gayed B, Darwish O, Youssef R, John G, Harrow B, Jacobs CD, Gaitonde M, Sagalowsky A, Shariat S, Lotan Y, Kapur P, Margulis V. Prospective Analysis of Ki-67 as an Independent Predictor of Oncologic Outcomes in Patients with High Grade Upper Tract Urothelial Carcinoma. Journal of Urology. 2014 Jan; 191(1):28-34.
- Straka C, Kim DN, Timmerman R, Pedrosa I, Jacobs CD, Brugarolas J. Ablation of a Site of Progression with Stereotactic Body Radiation Therapy Extends Sunitinib Treatment from 14 to 22 Months. Journal of Clinical Oncology. 2013 Aug; 31(23):e401-3.
- Jacobs CD, Kim DN, Timmerman R, Straka C, Brugarolas J. Prolonged Survival of a Patient with Papillary Renal Cell Carcinoma and Brain Metastases Using Pazopanib. Journal of Clinical Oncology. 2013 Mar; 31(7): e114-7.
- Yu L, Tumati V, Tseng S, Hsu F, Kim DN, Hong D, Hsieh JT, Jacobs CD, Kapur P, Saha D. DAB2IP Regulates Autophagy in Prostate Cancer in Response to Combined Treatment of Radiation and a DNA- PKcs Inhibitor. Neoplasia. 2012 Dec; 14(12):1203-12.
Abstracts
- Kelsey CL, Jacobs CD, Williamson H, Behrens S, Hsu D, Willett CG, Mantyh CR, Suneja G, Czito BG. Differences in Clinicopathologic Features and Response to Neoadjuvant Radiotherapy for Early- Versus Late-Onset Stage II-III Rectal Adenocarcinoma. Int J Radiat Oncol Biol Phys. 2020 Nov; 108(3S): E623.
- Jacobs CD, Chodavadia PA, Wang F, Salama JK, Kelsey CR, Clarke JW, Ready NE, Torok JA. Analysis of Synergy Between Early-Incorporation Immunotherapy and Extracranial Radiotherapy in Stage IV Non-Small Cell Lung Cancer. Journal of Immunotherapy of Cancer. 2019 Nov; 7(1S):P820.
- Jacobs CD, Gao J, Wang X, Mehta K, Salama JK, Torok JA, Kelsey CR. Nomogram Predicting Overall Survival Benefit of Stereotactic Ablative Radiotherapy for Early Stage Non-Small Cell Lung Cancer. Journal of Thoracic Oncology. 2019 Oct; 14(10S):S611.
- Jacobs CD, Kahmke R, Rocke D, Barak I, Jung SH, Suneja G, Mowery YM. Nomogram to Predict Survival Benefit of Postoperative Radiotherapy for Major Salivary Gland Cancers. International Journal of Radiation Oncology ∙ Biology ∙ Physics. 2019 Sept; 105(1S):S183.
- Jacobs CD, Barbour AB, Suneja G, Williamson H, Floyd SR, Torok JA, Kirkpatrick JP. Whole Brain Radiotherapy Practice Patterns in the Era of Stereotactic Radiosurgery. International Journal of Radiation Oncology ∙ Biology ∙ Physics. 2019 Sept; 105(1S):E576-77.
- Price J, Shantzer L, Jacobs CD, Niedzwiecki D, Clarke JM, Kelsey CR, Salama JK, Torok JA. Radiation Therapy Prior to Immune Checkpoint Inhibition in Metastatic Non-Small Cell Lung Cancer: Determining Toxicity and Efficacy of Combination Treatment. International Journal of Radiation Oncology ∙ Biology ∙ Physics. 2019 Sept; 105(1S):E527.
- Lafata K, Gao J, Jacobs CD, Wang X, Kelsey CR, Yin FF, Corradetti M. Identification of Radiomic Biomarkers for Locally Advanced Lung Cancer. International Journal of Radiation Oncology ∙ Biology ∙ Physics. 2019 Sept; 105(1S):E515.
- Jacobs CD, Woldemichael K, Williamson H, Abisheva Z, Howell E, Abdelgadir J, Dechant C, Floyd SR, Fecci P, Kirkpatrick JP, Adamson J, Torok JA. Single- Versus Multi-Fraction Stereotactic Radiosurgery for Brainstem Metastases. Neuro-Oncology Advances. 2019 Aug; 1S:i22.
- Jacobs CD, Chodavadia P, Wang F, Havrilesky L, Chino JP, Suneja G. United States Practice Patterns and Comparative Effectiveness of GOG 249 Arms. Brachytherapy. 2019 Jun; 18(3):S59-60.
- Jacobs CD, Suneja G, Barak I, Mehta K, Agassi A, Brizel DM, Mowery YM. Utilization of Brachytherapy for Early Stage Oral Cavity Cancers in the United States. Brachytherapy. 2019 Jun; 18(3):S29.
- Barbour AB, Jacobs CD, Suneja G, Floyd SR, Torok JA, Kirkpatrick JP. United States Radiotherapy Practice Patterns for Brain Metastases in the Era of Stereotactic Radiosurgery. Journal of Radiosurgery & SBRT. 6(S6.1): a25-1.
- Jacobs CD, Rocke D, Kahmke R, Williamson H, Suneja G, Mowery YM. Adjuvant Radiotherapy is Associated with Improved Overall Survival for Resected Alveolar Ridge Squamous Cell Carcinoma with Adverse Pathologic Features. Journal of National Comprehensive Cancer Network. 2019 Mar; 17(3.5):HSR19-092.
- Jacobs CD, Gao J, Wang X, Ready NE, Clarke JM, Tong B, Kelsey CR, Suneja G, Torok JA. Definitive Radiotherapy for Inoperable Stage IIB Non-Small Cell Lung Cancer: Patterns of Care and Comparative Effectiveness Analyses Using the National Cancer Database. International Journal of Radiation Oncology ∙ Biology ∙ Physics. 2019 May; 104(1):243.
- Jacobs CD, Trotter J, Palta M, Wu Y, Willett CG, Lee WR, Czito BC. Multi-Institutional Analysis of Synchronous Prostate and Rectosigmoid Cancers. Journal of Clinical Oncology. 2019 Mar; 37(7S):33.
- Jacobs CD, Carpenter DJ, Chino JP. Changes on Mid-Treatment FDG-PET/CT for Cervical Cancer Treated with Chemoradiotherapy Are Associated with Prognosis. International Journal of Radiation Oncology ∙ Biology ∙ Physics. 2018 Nov; 102(3S):S221.
- Jacobs CD, Carpenter DJ, Hong JC, Chino JP. Inclusion of Subjects with Internally Inconsistent or Anomalous Data within the National Cancer Database Significantly Alters Survival Results. International Journal of Radiation Oncology ∙ Biology ∙ Physics. 2018 Nov; 102(3S):S158-9.
- Jacobs CD, Hong JC, Havrilesky L, Sosa JA, Chino JP. Quality of reported radiation data as recorded in the NCDB for node positive uterine cancer. International Journal of Radiation Oncology ∙ Biology ∙ Physics. 2017 Oct; 99(2S):E296.
- Jacobs CD, Loudas N, Driscoll C. Toxicity Analysis of Lung Stereotactic Body Radiation Therapy (SBRT) at a Community Hospital. Journal of Radiation Oncology. 2017 Sept; 6(3):225-45.
- Jacobs CD, Jafari ME. How Low is Low? Radiation Dose Assessment of Low Dose Chest Computed Tomography for Lung Cancer Screening. Journal of Radiation Oncology. 2017 Sept; 6(3):225-45.
- Jacobs CD, Borgert A, Jafari ME. Early Results of Lung Cancer Screening by Low-Dose Computed Tomography at a Community Hospital. International Journal of Radiation Oncology ∙ Biology ∙ Physics. 2016 Oct; 96(2S):E458-E459.
- Jacobs CD, Tumati V, Kapur P, Yan J, Xie X, Hannan R, Hsieh JT, Kim DW, Saha D. Association of Decreased Tumor DAB2IP and High-Risk Prostate Cancer-Specific Survival. Journal of Clinical Oncology. 34, 2016 Jun; 34(15S): e16553.
- Tumati V, Jacobs CD, Ying J, Roehrborn CG, Lotan Y, Margulis V, Pistenmaa D, Kim DW, Hannan R. Outcomes in High-Risk Prostate Cancer Patients Treated with Definitive Versus Adjuvant Radiation Therapy. Journal of Clinical Oncology. 2016 Jan; 34(2S):133.
- Hodges JC, Meyer J, Beg, MS, Jacobs CD, Timmerman R. Cost Effectiveness Analysis of Stereotactic Ablative Radiotherapy (SABR) Versus Radiofrequency Ablation (RFA) for Inoperable Liver Metastases. Texas Radiological Society’s 101st Annual Meeting: Radiation Oncology & Physics Program. Abstract. 2014 Mar 1; Plano, TX.
- Chun S, Jacobs CD, Yan J, Xie X, Choe K, Hannan R, Pistenmaa D, Lotan Y, Roehrborn C, Kim DN. The Effects of Anticoagulant Use in High-Risk Prostate Cancer Treated with Radiotherapy on Overall Survival and Biochemical Control. Journal of Clinical Oncology. 2014 Feb; 32(S4):146.
- Jacobs CD, Kapur P, Yan J, Tumati V, Xie X, Pistenmaa D, Bhuiyan M, Hsieh JT, Saha D, Kim DN. DAB2IP Pathway Protein Status in High-Risk Prostate Cancer Correlates with Outcomes for Patients Following Radiation Therapy. UT Southwestern Medical Student Research Forum. 2014 Feb; 52:46.
- Jacobs CD, Kapur P, Yan J, Tumati V, Xie X, Pistenmaa D, Bhuiyan M, Hsieh JT, Saha D, Kim DN. Tumor Status of DAB2IP But Not EZH2 Correlates with Biochemical Failure, Castrate Resistance, and Distant Metastases in High-risk Prostate Cancer Patients Treated with Radiation Therapy. International Journal of Radiation Oncology ∙ Biology ∙ Physics. 2013 Oct; 87(2):S664-5.
- Jacobs CD, Tumati V, Hong D, Kapur P, Pistenmaa D, Xie X, Hsieh JT, Saha D, Kim DN. Reduction of DAB2IP Correlates with Increased Biochemical Failure in High-Risk Prostate Cancer Patients Treated with Radiation Therapy. UT Southwestern Medical Student Research Forum. 2013 Jan; 51:57.
- Jacobs CD, Yan J, Pistenmaa D, Choe K, Kim DN. Anticoagulant Use is Associated with Improved Biochemical Control of High-Risk Prostate Cancer Patients Treated with Radiation Therapy. UT Southwestern Medical Student Research Forum. 2013 Jan; 51:58.
- Kim DN, Tumati V, Pistenmaa D, Kapur P, Xie X, Hannan R, Jacobs CD, Straka C, Hsieh JT, Saha D. Loss of Tumor Suppressor DAP2IP Correlates with Decreased Biochemical Recurrence Free Survival in Highrisk Prostate Cancer Patients Treated with Radiation Therapy. International Journal of Radiation Oncology ∙ Biology ∙ Physics. 2012 Nov; 84(3):S714.